Antimicrobial Therapy

Photodynamic Inactivation of Endopathogenic Microbiota Using Curcumin- mediated Antimicrobial Photodynamic Therapy

Root canal disinfection is one of the main factors governing success of endodontic therapy. Antimicrobial photodynamic therapy (aPDT) is presented as a promising antimicrobial therapy that can eliminate microbiota present in infected root canal systems. In this study, a series of experiments investigated the effects of aPDT on cell viability and biofilm degradation ability of endopathogenic mic...

Awareness and perception of multidrug-resistant organisms and antimicrobial therapy among internists vs. surgeons of different specialties: Results from the German MR2 Survey

Microbial Etiology and Antimicrobial Susceptibility of Bactria Implicated in Urinary Tract Infection in Tehran, Iran

Background and Objectives: Urinary tract infections (UTI) are one of the most common infectious diseases with different microbial agent and antimicrobial resistant pattern in hospitalized patients and outpatients. In order to assess the adequacy of therapy, knowledge of prevalence and resistance pattern of the bacteria is necessary. The main aim of this study was to evaluate the prevalence and ...

An Increase in Antimicrobial Effects of Standard Antibiotics in Combination with the Active Metabolites Isolated from Marine Streptomyces: A Laboratory Study

Background and Objectives: Combination therapy has been considered as a potential approach to overcome antimicrobial resistance. In this study the antimicrobial effects of active compounds produced by some marine Streptomyces spp. in combination with some standard antibiotics against multidrug-resistant pathogens was investigated. Materials and Methods: In this laboratory study, the bacteria i...

Antimicrobial treatment of ventilator-associated pneumonia.

Ventilator-associated pneumonia is a common complication of ventilatory support for patients with acute respiratory failure and is associated with increased morbidity, mortality, and costs. Optimal antimicrobial therapy is an essential part of successful management of ventilator-associated pneumonia. Numerous safe and effective antimicrobial drugs are available, and their efficacy can be optimi...

Bloodstream Infection: The Influence of Risk Factors, Etiology and Antimicrobial Therapy on Mortality Rates

Introduction: Inappropriate initial antimicrobial therapy leads to higher mortality in patients with bloodstream infection. This study aimed to evaluate the relationship between risk factors, etiology and antimicrobial therapy on mortality rates of patients with bloodstream infection. Methods: Between January 2016 to December 2016, 167 patients with bloodstream infection were prospectively eval...